M-2450
Abz-tBu-Gly-tBu-Gly-Asn(Me)2-Ala-Ser-Ser-Arg-Leu-3-nitro-Tyr-Arg-OH
Trifluoroacetate salt
Synonym:
Abz-Tle-Tle-Asn(Me)2-Ala-Ser-Ser-Arg-Leu-3-nitro-Tyr-Arg-OH
| C61H97N19O18 | Mr: 1384.56 | [204909-37-5] net |
| Longterm storage temperature: | -20 ± 5 °C | C61H97N19O18 |
Improved fluorogenic substrate for the determination of human cytomegalovirus protease. The FRET substrate displayed a kcat/Km value of 15940 M-1 s-1, i.e., more than 60-fold greater than that of the equivalent, non-optimized substrate Abz-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-3-nitro-Tyr-Arg-OH under identical conditions.
Literature:
P.R.Bonneau et al., Anal. Biochem., 255, 59 (1998)
P.R.Bonneau et al., Anal. Biochem., 255, 59 (1998)
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