Caspase Inhibitors and Substrates
Nomenclature of Caspases (Cysteine-dependent aspartate-directed proteases):
Caspase-1 ... ICE
Caspase-2 ... ICH-1
Caspase-3 ... CPP-32, Yama, Apopain
Caspase-4 ... TX, ICH-2, ICErel-II
Caspase-5 ... ICErel-III, TY
Caspase-6 ... Mch2
Caspase-7 ... Mch3, ICE-LAP3, CMH-1
Caspase-8 ... MACH, FLICE, Mch5
Caspase-9 ... ICE-LAP6, Mch6
Caspase-10 ... Mch4
Family Literatur:
E.S.Alnemri et al., Cell, 87, 171 (1996)
G.M.Cohen, Biochem. J., 326, 1 (1997)
D.K.Miller, Semin. Immunol., 9, 35 (1997)
D.W.Nicholson and N.A.Thornberry, Trends Biochem. Sci., 22, 299 (1997)
N.Margolin et al., J. Biol. Chem., 272, 7223 (1997)
R.V.Talanian et al., J. Biol. Chem., 272, 9677 (1997)
B.B.Wolf et al., J. Biol. Chem., 274, 20049 (1999)
R.V.Talanian et al., J. Med. Chem., 43, 3351 (2000)
U.Fischer et al., Cell Death Differ., 10, 76 (2003)
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