Rat amylin (rIAPP) lacks the fibril-forming capacity of human amylin (hIAPP). As a consequence, toxic effects have been reported for the human but not for the rat peptide.
The sequence of H-9475 is identical to mouse IAPP.
H-9475
Amylin (mouse, rat)
H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
(Disulfide bond)
Synonym:
IAPP (mouse, rat), Islet amyloid polypeptide (mouse, rat)
| C167H272N52O53S2 | Mr: 3920.45 | [124447-81-0] |
| Longterm storage temperature: | -20 ± 5 °C | C167H272N52O53S2 |
Literature:
J.D.Leffert et al., Proc. Natl. Acad. Sci. USA, 86, 3127 (1989)
H.A.Golpon et al., Peptides, 24, 1157 (2003)
J.Green et al., J. Mol. Biol., 326, 1147 (2003)
J.D.Leffert et al., Proc. Natl. Acad. Sci. USA, 86, 3127 (1989)
H.A.Golpon et al., Peptides, 24, 1157 (2003)
J.Green et al., J. Mol. Biol., 326, 1147 (2003)
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