E-3745
H-Arg(Me)-OH
Acetate salt
Also available as cGMP API.
Synonym:
L-NMMA, Tilarginine, Targinine
| C7H16N4O2 | Mr: 188.23 | [17035-90-4] net |
| Longterm storage temperature: | -20 ± 5 °C | C7H16N4O2 |
Cell-permeable inhibitor of all three isoforms of nitric oxide synthase: Ki 650 nM (nNOS), 700 nM (eNOS), 9500 nM (iNOS).
Literature:
D.W.Reif and S.A.McCreedy, Arch. Biochem. Biophys., 320, 170 (1995)
A.J.Hobbs et al., Annu. Rev. Pharmacol. Toxicol., 39, 191 (1999)
S.Midha et al., Biochem. Biophys. Res. Commun., 336, 346 (2005)
D.W.Reif and S.A.McCreedy, Arch. Biochem. Biophys., 320, 170 (1995)
A.J.Hobbs et al., Annu. Rev. Pharmacol. Toxicol., 39, 191 (1999)
S.Midha et al., Biochem. Biophys. Res. Commun., 336, 346 (2005)
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Family Description:
See also E-2770, H-Arg(Me)-OH · HCl, in the subfamily 'Arginine Substrates and Inhibitors'.
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