H-6446
(Glu20)-Amyloid β-Protein (1-42)
H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Glu-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
Synonym:
Amyloid β-Protein (1-42) F20E
| C199H309N55O62S | Mr: 4496.04 | |
| Longterm storage temperature: | -20 ± 5 °C | C199H309N55O62S |
The Aβ F20E mutant forms fibrils in vitro although much slower than the wild-type Aβ 1-42. In vivo, deposits of F20E have not been observed, possibly due to the retarded aggregation which permits concomitant enzymatic degradation.
Literature:
L.M.Luheshi et al., PLoS Biology, 5, e290 (2007)
L.M.Luheshi et al., PLoS Biology, 5, e290 (2007)
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Family Description:
See also β-Secretase Inhibitors and Substrates.
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