Shopping Cart - CHF 0.00

You have no items in your shopping cart.

Return to Previous Page

Availability: In stock

Fmoc-Asp-allyl ester

B-2715

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
B-2715.0001 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 82.00
CHF 76.26 (7%)
B-2715.0005 5 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 309.00
CHF 287.37 (7%)
Add to Wish List
Add to Compare

Details

α-Allyl esters are useful tools for the on-resin head-to-tail cyclization of peptides and for the synthesis of side-chain lactam peptides, glyco- and sulfo-peptides, and branched peptides. Allyl esters are cleaved under mild conditions using Pd(0). These conditions are compatible with Fmoc- and Boc-SPPS.
The Asp α-Allyl esters show a somewhat higher propensity for base-catalyzed aspartimide formation than the corresponding β-esters.
Fmoc-Asp-OAll is a versatile educt for synthesizing complex Asp and Asn derivatives, e.g., N-glycosylated Asn building blocks.
Item Number 4019715
Synonyms Fmoc-Asp-OAll
Molecular Formula C₂₂H₂₁NO₆
Relative Molecular Mass 395.41
CAS Registry Number [144120-53-6]
Storage Conditions -20 ± 5 °C

Product citations

M.A.Bonache et al., Tetrahedron Lett., 50, 4151 (2009)
F.Albericio et al., Peptides 1992, Proceedings of the 22nd European Peptide Symposium, Interlaken, Switzerland, p. 191, C.H.Schneider and A.N.Eberle, eds., Escom, Leiden, (1993)