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Fmoc-Glu(2-phenylisopropyl ester)-OH

B-2500

Product No. Pack Size Available ADS InfoAnalytical Data Sheet Unit Price Online Order Price Qty
B-2500.0001 1 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 190.00
CHF 176.70 (7%)
B-2500.0005 5 g Ships within 1 business day ADSExemplary Data Sheet of a current available lot.
CHF 760.00
CHF 706.80 (7%)
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Details

Glu-derivative for the selective modification of the γ-carboxyl group. The OPp group can be removed selectively in the presence of Boc/OtBu with 1% TFA/DCM. Ocampo et al. applied OPp protection during the synthesis of a peptide-oligonucleotide conjugate and cleaved it with 3% trichloroacetic acid in DCM. Tofteng et al. generated a backbone pyroglutamyl imide moiety from C-terminal Glu after selective on-resin OPp removal.
Item Number 4025419
Synonyms Fmoc-Glu(OPp)-OH, Fmoc-Glu(O-2-PhiPr)-OH
Molecular Formula C₂₉H₂₉NO₆
Relative Molecular Mass 487.55
CAS Registry Number [200616-39-3]
Storage Conditions -20 ± 5 °C

Product citations

F.Dick et al., Peptides 1996, Proceedings of the 24th European Peptide Symposium, Edinburgh, Scotland, p. 339, R.Ramage and R.Epton, eds., Mayflower Scientific Ltd., England, (1998)